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ORIGINAL ARTICLE
Application of infrared and nuclear magnetic resonance spectra in studying the bacterial efficacy of some oxazepane derivatives derived from hydrazones
Abdul Wahed Abdul Sattar Talluh 1
,
 
Mohammed Jwher Saleh 2
,
 
Jamil Nadhem Saleh 3
 
 
 
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1
Tikrit University, College of Basic Education, Shirqat, Tikrit University, Iraq
 
2
Supervision, Salah al-Din Education Directorate, Iran
 
3
Supervision, Salah al-Din Education Directorate, Iraq
 
 
Submission date: 2024-09-03
 
 
Final revision date: 2024-09-29
 
 
Acceptance date: 2024-09-29
 
 
Publication date: 2024-09-29
 
 
Corresponding author
Abdul Wahed Abdul Sattar Talluh   

Tikrit University, College of Basic Education, Shirqat, Tikrit University, Iraq
 
 
Sensors and Machine Learning Applications 2024;3(3)
DOI: https://doi.org/10.69534/smla/193913
 
 
Article (PDF)
References (39)
 
KEYWORDS
biological activity
triazole
Infrared spectra
hydrazide
hydrazone
oxazepane
 
TOPICS
Recent Advancements in Remote Sensing
 
ABSTRACT
This research included the utilisation of infrared and nuclear magnetic resonance spectra in studying and preparing new derivatives of the oxazepan ring by a series of reactions, where the triazole ring was prepared from the reaction of the carboxylic acid with carbothiohydrazide, and from the resulting reaction (triazole) with aqueous hydrazine. The latter was reacted with benzaldehyde compensators to prepare hydrazones, which is the basic intermediate for the preparation of the oxazepan ring. The hydrazones were reacted with succinic anhydride, and the validity of the structures was proven using infrared and nuclear magnetic resonance spectra of proton and carbon. Its biological activity has also been tested for two species of Gram-positive bacteria, Staphylococcus epidermidis and Gram-negative Klebsiella pneumoniae.
 
REFERENCES (39)
1.
Khairallah, B. A., Muhammad, F. M., Saleh, J. N., & Saleh, M. J. (2024). Preparation, Characterisation, Biological Activity Evaluation, and Liquid Crystallography Study of New Diazepine Derivatives. World of Medicine: Journal of Biomedical Sciences, 1(7), 65-76.‏.
Google Scholar
 
 
2.
Talluh, A. W. A. S., Saleh, M. J., & Saleh, J. N. (2024). Preparation, Characterisation and Study of the Molecular Docking of Some Derivatives of the Tetrazole Ring and Evaluation of their Biological Activity. World of Medicine: Journal of Biomedical Sciences, 1(7), 15-23.‏.
Google Scholar
 
 
3.
Sathish Kumar, S., & P Kavitha, H. (2013). Synthesis and biological applications of triazole derivatives–a review. Mini-Reviews in Organic Chemistry, 10(1), 40-65.‏.
Google Scholar
 
 
4.
Kumar, S., Khokra, S. L., & Yadav, A. (2021). Triazole analogues as potential pharmacological agents: A brief review. Future Journal of Pharmaceutical Sciences, 7(1), 106.‏.
Google Scholar
 
 
5.
Abdul Wahed, A. S. T. (2024). Preparation and Evaluation of Bacterial Activity and Study of the Crystalline Properties of Some 1, 3-Oxazepine-4, 7-Dione Derivatives. Central Asian Journal of Theoretical and Applied Sciences, 5(2), 15-26.‏.
Google Scholar
 
 
6.
Shaima H. Abdullah et al. (2024). Synthesis, Characterisation and Antibacterial Evaluation of Novel Thiazolidine Derivatives, Journal of Angiotherapy, 8(3), 1-9, 9501.
Google Scholar
 
 
7.
Najim, D. M., Al-badrany, K. A., & Saleh, M. K. Synthesis of some new oxazepine compounds derived from cyanoethyl acetate and study their inhibitory activity against some pathogenic bacterial species. Unpublished.‏.
Google Scholar
 
 
8.
Muhammad, F. M., Khairallah, B. A., & Albadrany, K. A. (2024). Synthesis, characterisation and Antibacterial Evaluation of Novel 1, 3-Oxazepine Derivatives Using A Cycloaddition Approach. Journal of Angiotherapy, 8(3), 1-5.‏.
Google Scholar
 
 
9.
Al-Jubori, H. M. S. (2024). Preparation and Characterisation of Some 1, 3-Oxazepane-7, 4-Dione Derivatives and Evaluation of their Biological Activity. EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE, 4(4), 333-343.‏.
Google Scholar
 
 
10.
Kwiecien, H., Smist, M., & Wrzesniewska, A. (2012). Synthesis of aryl-fused 1, 4-oxazepines and their oxo derivatives: A Review. Current Organic Synthesis, 9(6), 828-850.‏.
Google Scholar
 
 
11.
Sager, A. G., Abaies, J. K., & Katoof, Z. R. (2023). Molecular Docking, Synthesis and Evaluation for Antioxidant and Antibacterial Activity of New Oxazepane and Benzoxazepine Derivatives. Baghdad Science Journal.‏.
Google Scholar
 
 
12.
Dorababu, A. (2023). Update of Recently (2016–2020) Designed Azepine Analogs and Related Heterocyclic Compounds with Potent Pharmacological Activities. Polycyclic Aromatic Compounds, 43(3), 2250-2268.‏.
Google Scholar
 
 
13.
Hassan, S. A., Aziz, D. M., Abdullah, M. N., Bhat, A. R., Dongre, R. S., Ahmed, S., ... & Jamalis, J. (2023). Design and synthesis of oxazepine derivatives from sulfonamide Schiff bases as antimicrobial and antioxidant agents with low cytotoxicity and hemolytic prospective. Journal of Molecular Structure, 1292, 136121.‏.
Google Scholar
 
 
14.
Demaray, J. A., Thuener, J. E., Dawson, M. N., & Sucheck, S. J. (2008). Synthesis of triazole-oxazolidinones via a one-pot reaction and evaluation of their antimicrobial activity. Bioorganic & medicinal chemistry letters, 18(17), 4868-4871.‏.
Google Scholar
 
 
15.
Khurshid, M. N., Jumaa, F. H., & Jassim, S. S. (2022). Synthesis, characterisation, and evaluation of the biological activity of tetrazole compounds derived from the nitrogenous base uracil. Materials Today: Proceedings, 49, 3630-3639.‏.
Google Scholar
 
 
16.
Talluh, A. W. A. S., Saleh, J. N., & Saleh, M. J. (2024). Preparation, Characterisation and Evaluation of Biological Ac-tivity and Study of Molecular Docking of Some New Thiazoli-dine Derivatives.‏.
Google Scholar
 
 
17.
Jumaa, F. H., & Shawkat, S. M. (2022, November). Synthesis, assess biological activity and laser efficacy of some new bis-1, 3-oxazepene 4, 7-dione derivatives. In AIP Conference Proceedings (Vol. 2394, No. 1). AIP Publishing.‏.
Google Scholar
 
 
18.
Dalaf, A. H., Saleh, M. J., & Saleh, J. N. (2024). Green Synthesis, Characterization, And Multifaceted Evaluation Of Thiazolidinone Derivatives: A Study On Biological And Laser Efficacy. European Journal of Modern Medicine and Practice, 4(7), 155-168.
Google Scholar
 
 
19.
‏Saleh, M. J., Saleh, J. N., & Al-Badrany, K. (2024). Preparation, characterisation, and evaluation of the biological activity of pyrazoline derivatives prepared using a solid base catalyst. European journal of modern medicine and practice, 4(7), 25-32.‏.
Google Scholar
 
 
20.
Saleh, J. N., & Khalid, A. (2023). Synthesis, characterisation and biological activity evaluation of some new pyrimidine derivatives by solid base catalyst AL2O3-OBa. Central Asian Journal of Medical and Natural Science, 4(4), 231-239.‏.
Google Scholar
 
 
21.
Talluh, A. W. A. S., Saleh, M. J., Saleh, J. N., Al-Badrany, K., & mohammed saleh Al-Jubori, H. (2024). Preparation, characterisation, and evaluation of the biological activity of new 2, 3-dihydroquinazoline-4-one derivatives. EUROPEAN JOURNAL OF MODERN MEDICINE AND PRACTICE, 4(4), 326-332.‏.
Google Scholar
 
 
22.
Talluh, A. W. A. S. (2024). Preparation, Characterisation, Evaluation of Biological Activity, and Study of Molecular Docking of Azetidine Derivatives. Central Asian Journal of Medical and Natural Science, 5(1), 608-616.‏.
Google Scholar
 
 
23.
Saleh, M. J., & Al-Badrany, K. A. (2023). Preparation, characterisation of new 2-oxo pyran derivatives by AL2O3-OK solid base catalyst and biological activity evaluation. Central Asian Journal of Medical and Natural Science, 4(4), 222-230.‏.
Google Scholar
 
 
24.
Muhammad, F. M., Khairallah, B. A., Saleh, M. J., & Saleh, J. N. (2024). Preparation and Characterisation of New Rings of Oxazine Derivatives and Studying Their Biological and Laser Effectiveness and Molecular Docking. Central Asian Journal of Theoretical and Applied Science, 5(4), 190-201.
Google Scholar
 
 
25.
Shah, M. A., Uddin, A., Shah, M. R., Ali, I., Ullah, R., Hannan, P. A., & Hussain, H. (2022). Synthesis and characterisation of novel hydrazone derivatives of isonicotinic hydrazide and their evaluation for antibacterial and cytotoxic potential. Molecules, 27(19), 6770.‏.
Google Scholar
 
 
26.
de Oliveira Carneiro Brum, J., França, T. C., LaPlante, S. R., & Villar, J. D. F. (2020). Synthesis and biological activity of hydrazones and derivatives: A review. Mini reviews in medicinal chemistry, 20(5), 342-368.‏.
Google Scholar
 
 
27.
Vessally, E., Hosseinian, A., Edjlali, L., Bekhradnia, A., & Esrafili, M. D. (2016). New route to 1, 4-oxazepane and 1, 4-diazepane derivatives: synthesis from N-propargylamines. RSC advances, 6(102), 99781-99793.‏.
Google Scholar
 
 
28.
Sattar Talluh, A. W. A., Saleh, J. N., Saleh, M. J., & Saleh Al-Jubori, H. M. (2024). Preparation and Characterisation of New Imidazole Derivatives Derived From Hydrazones and Study of their Biological and Laser Efficacy. Central Asian Journal of Theoretical and Applied Science, 5(4), 202-211.
Google Scholar
 
 
29.
Saleh, M. M., Saleh, J. N., Rokan, F. F., & Saleh, M. J. (2024). Synthesis, Charactarizit and evaluation of bacterial efficacy and study of molecular substrates of cobalt (II) complex [Co (2-(benzo [d] thiazol-2-yloxy) acetohydrazide)(H2O)(Cl2)]. Central Asian Journal of Medical and Natural Science, 5(4).‏.
Google Scholar
 
 
30.
Talluh, A. W. A. S., Saleh, M. J., Saleh, J. N., & Al-Jubori, H. M. S. (2024). Synthesis and Characterisation of Some New Imine Graphene Derivatives and Evaluation of Their Biological Activity. Central Asian Journal of Medical and Natural Science, 5(4), 272-290.
Google Scholar
 
 
31.
Al-Joboury, W. M., Al-Badrany, K. A., & Asli, N. J. (2022, November). N-alkylation of substituted 2-amino benzothiazoles by 1, 4-bis (bromo methyl) benzene on mixed oxides at room temperature and study their biological activity. In AIP Conference Proceedings (Vol. 2394, No. 1). AIP Publishing.‏.
Google Scholar
 
 
32.
Al-Joboury, W. M., Al-Badrany, K. A., & Asli, N. J. (2021). Synthesis of new azo dye compounds derived from 2-aminobenzothiazole and study their biological activity. Materials Today: Proceedings, 47, 5977-5982.‏.
Google Scholar
 
 
33.
Saleh, R. H., Rashid, W. M., Dalaf, A. H., Al-Badrany, K. A., & Mohammed, O. A. (2020). Synthesis of some new thiazolidinone compounds derived from schiff bases compounds and evaluation of their laser and biological efficacy. Ann Trop & Public Health, 23(7), 1012-1031.‏.
Google Scholar
 
 
34.
Abdullah, S. H., Salih, M. M., & Khalid, A. Synthesis, Characterization and Antibacterial Evaluation of Novel Thiazolidine Derivatives.‏.
Google Scholar
 
 
35.
Al-Tufah, M. M., Jasim, S. S., & Al-Badrany, K. A. (2020). Synthesis and Antibacterial Evaluation of some New Pyrazole Derivatives. Prof.(Dr) RK Sharma, 20(3), 178.‏.
Google Scholar
 
 
36.
Al Rashidy, A. A. M., Al Badrany, K. A., & Al Garagoly, G. M. (2020, August). Spectrophotometric determination of sulphamethoxazole drug by new pyrazoline derived from 2, 4-dinitro phenyl hydrazine. In Materials Science Forum (Vol. 1002, pp. 350-359). Trans Tech Publications Ltd.‏.
Google Scholar
 
 
37.
Al-Joboury, N. A., Al-Badrany, K. A., Hamed, A. S., & Aljoboury, W. M. (2019). Synthesis Of Some New Thiazepine Compounds Derived From Chalcones And Evaluation There Biochemical And Biological Activity. Biochemical & Cellular Archives, 19(2).
Google Scholar
 
 
38.
Al-Badrany, K. A., Mohammed, A. S., & Alasadi, Y. K. (2019). Synthesis of some new 1, 3, 4-oxadiazole compounds derived from 1H-imidazole and study their biological activity. Eurasian Journal of Biosciences, 13(1), 501-507.‏.
Google Scholar
 
 
39.
Al-Badrany, K. A. (2024). The use of 2-aminopyrazine as a basic nucleophile for the preparation of new derivatives of the 5, 6-dihydropyridine-2 (1h)-ylidene) cyanamide ring, their diagnosis, and evaluation of their bacterial efficacy. European journal of modern medicine and practice, 4(5), 508-518.‏.
Google Scholar
 
 
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